Bioinformatics Evaluation and Signaling Network Analysis of Total Target mRNA and Related SNP Function in People with Gastric Cancer

Introduction: Stomach cancer is the fourth most common and second leading cause of death in world. In addition to significant costs, it imposes many problems on families that a proper justification for identifying related biomarkers. Method : The miRBASE website was used find bioinformatics information. addition, mirWALK miRNASN databases were searched miRNAs To pathways, DAVID KEGG adopted. Results: studies conducted first pathway reported microRNA has -miR - 10a -3p, through binding rs1049216 CASP3 gene, by exerting an inhibitory effect this prevents development cancer. pathway, -296 rs1564483 BCL2 causes third -194 rs7177 CCND1 Conclusion: research, pathways involved predicted. By finding three SNPs specific regions above -said genes, we found these can be stomach introduced as biological biomarkers .